Where does filtration occur in the nephron?

Where does filtration occur in the nephron?

• A. Bowman's capsule
• B. Loop of Henle
• C. Collecting duct
• D. Distal tubule

Answer: (A)

Filtration happens at the renal corpuscle, specifically in the glomerulus inside Bowman's capsule. Blood pressure pushes water and small solutes through the filtration barrier—composed of the glomerular endothelium, the basement membrane, and podocyte slit diaphragms—into Bowman's space, forming the filtrate. Larger proteins and cells stay behind in the blood. The filtrate then enters the proximal tubule for reabsorption and secretion; the Loop of Henle, distal tubule, and collecting duct handle reabsorption, secretion, and final urine concentration rather than filtration.

Filtration happens at the renal corpuscle, specifically in the glomerulus inside Bowman's capsule. Blood pressure pushes water and small solutes through the filtration barrier—composed of the glomerular endothelium, the basement membrane, and podocyte slit diaphragms—into Bowman's space, forming the filtrate. Larger proteins and cells stay behind in the blood. The filtrate then enters the proximal tubule for reabsorption and secretion; the Loop of Henle, distal tubule, and collecting duct handle reabsorption, secretion, and final urine concentration rather than filtration.